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In a study of semaglutide efficacy, the average reduction in weight from baseline was 10.2%, but 4.9% of patients achieved over 25% reduction from baseline, and 32.2% achieved less than a 5% reduction from baseline or even weight gain 5
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New research from Blue Cross Blue Shield reveals that, among 170,000 patients using a GLP-1 for weight management, 58% discontinued use before reaching a clinically meaningful health benefit
March 18, 2026
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