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Vitamin C deficiency is rare in developed countries
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Prx3 homodimer has a redox-sensitive cysteine that upon reaction with H 2 O 2 is oxidized to Cys-SOH, which then reacts with neighboring Cys-SH of the other subunit to form an intermolecular disulfide that can be readily reduced by thioredoxin reductase 2 (TrxRD2
Hospitals worldwide use pharmaceutical-grade NAC as a life-saving antidote, which proves its potency and safety profile
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