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IARC Sci Publ 163:407419 Chen CCV, Chen YC et al (2013) Neurovascular abnormalities in brain disorders: highlights with angiogenesis and magnetic resonance imaging studies

B12 shots have been shown to boost mood, increase energy, and provide an improved sense of well-being

If constipation remains severe despite those interventions, or if you develop complications like hemorrhoids or fissures, discuss dose reduction with your provider