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Looking ahead, GLP-1 drugs are likely to play an even larger role in managing chronic conditions
Bitter Orange Extract Bitter orange extract is found in some citrus fruits and contains synephrine, a stimulant with effects similar to ephedrine (a dangerous ingredient banned by the FDA for use in diet and sports supplements because it showed to have serious health risks like heart attack and stroke, resulting in deaths), according to a 2022 review of the safety and efficacy of bitter orange extract in Nutrients
Most critically, patients with active malignancies or significant cancer risk factors may not be appropriate candidates due to the potential for promoting tumor growth and metastasis through angiogenesis stimulation
Altered incretin levels were also not associated with significant differences in postprandial insulin and glucose levels measured at the same time (Figure 1, I and J)
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