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Because MC1R is primarily involved in pigmentation biology, tanning response, and related skin signaling, this genotype is most informative for the pigment-related branch of the Melanotan II pathway rather than the central neuroendocrine receptors more directly involved in sexual-function signaling

While those medications primarily target GLP-1 receptors , Mounjaro acts on both GLP-1 and another hormone called GIP

"Plans with Weight Loss/Appetite Suppression Medication Coverage: Prior Authorization Notification." uhcprovider.com (PDF)