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The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings
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El cientfico estadounidense Kastin y el cientfico holands de Wied propusieron la opinin de que los pptidos podran cruzar la barrera hematoenceflica, sentando las bases para investigaciones posteriores sobre DSIP
Les tudes animales indiquent une demi-vie plasmatique denviron 1-2 heures, avec une distribution tissulaire rapide facilitant son rle dans la contraction des plaies et lpithlialisation
