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Stored fasting serum from participants was used to perform large-scale proteomic profiling using the SomaScan multiplex affinity assay

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Oxidative stress occurs when the body has too many unstable molecules called pro-oxidants free radicals and reactive oxygen species (ROS)

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Cell-based experiments also demonstrate receptor-dependent signaling changes when Retatrutide interacts with GLP-1R, GIPR, or GCGR expressing cells

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