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J., Holst, J

These experiments reveal the multi-faceted impact of RSL3-mediated inhibition of GPX4 in thyroid cancer cells, by altering DNA damage repair and proliferation signaling pathways, and suppressing thyroid tumor cell growth

Up to 80% of cirrhosis patients report poor sleep quality, as evidenced by Pittsburgh Sleep Quality Index (PSQI) scores exceeding 5 (ChildTurcottePugh [CTP] A: 16.9%, CTP B: 26.5%, and CTP C: 56.6%), and around 16 to 52% suffer from excessive daytime sleepiness (EDS), reflected by Epworth Sleepiness Scale (ESS) scores over 10 (CTP A: 17.6%, CTP B: 29.7%, CTP C: 52.8%) ( Insomnia, defined as difficulty initiating or maintaining sleep, is chiefly diagnosed through patient-reported symptoms

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