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Details of the FDA Ruling The FDA's decision, detailed in a March 10, 2025, update, specifies enforcement discretion periods for compounding Semaglutide: For 503A pharmacies (state-licensed), the FDA will not take action for violations related to Semaglutide's shortage list inclusion until April 22, 2025, or until the district court's decision on the preliminary injunction motion in Outsourcing Facilities Association (OFA) v

"This approval brings another important treatment option to people living with obesity," Novo Nordisk Chief Executive Mike Doustdar said in a statement, adding that a tablet may be simpler and more acceptable for some patients than injections

Furthermore, in another meta-analysis [23], which excluded ELIXA [24] due to fact that lixisenatide is a short-acting GLP-1RA and all participants had acute coronary syndrome, GLP-1RAs were associated with significant reductions in MACE (HR 0.85, 95% CI 0.800.90), cardiovascular death (HR 0.85, 95% CI 0.780.93), stroke (HR 0.81, 95% CI 0.740.90), and myocardial infarction (HR 0.88, 95% CI 0.810.96) (Table 2)

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