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It lists contraindications including personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, and severe pancreatitis, and says pregnancy, breastfeeding, and active diabetic retinopathy require specialist evaluation before treatment
Storage conditions directly impact how long semaglutide remains stable before opening
The observation that GI side effects concentrate at the first dose (rather than recurring with each injection) could improve the patient experience if confirmed in larger trials
Two doses spaced fewer than 3 days apart can stack the medication and increase side effects like nausea, vomiting, and low blood sugar
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