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Hepatic IGF-1 synthesis lags behind the growth hormone pulse by 6090 minutes, meaning endogenous IGF-1 levels peak 90150 minutes after the secretagogue dose

Most recently, the group of Cani and Delzenne showed that prebiotic fructo-oligosaccharides (FOS) attenuate experimental hepatic steatosis, possibly by modulating the intestinal microbiota or the intestinal barrier function or both [103]