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Independently tested
ApoE 4 has been demonstrated to impair cerebral insulin signaling by binding to the insulin receptor and preventing insulin receptor trafficking [151]
observed that CUR increased the cytotoxicity of MM U266 cell lines by increasing arsenic uptake in those cells with p53 mutations ( 3.6 Gallic acid GA, known by its chemical name 3,4,5-trihydroxy benzoic acid, comes from various natural sources, including bananas, strawberries, lemons, red wine, and green tea (Figure 2), GA has three hydroxyl groups attached to an aromatic ring in an ortho position, which explicitly provides its strong ability to scavenge ROS (Verma et al., 2013), which makes this compound particularly attractive to elucidate its mechanisms further