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While most people tolerate B12 shots well, it is always best to stay in communication with a qualified medical team
Other indications include malabsorption disorders (such as Crohn's disease or coeliac disease), following gastric surgery, strict vegan diets without supplementation, and certain medications that interfere with B12 absorption
Some lyophilization processes create denser powder requiring 5-10 minutes hydration before complete dissolution
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