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Further research should focus on conducting more clinical trials targeting specific OA subtypes (e.g., inflammatory OA) and investigating the combined use of TNF and IL-6 inhibitors with other therapies, such as stem cell therapy and chondroprotective agents

Occasionally, the end of the intestine that has been left in place will need to be brought to the skin's surface to allow waste excretion

Research in animal models has shown significant reductions in body weight and adipose tissue, with studies reporting up to 50% less weight gain in obese Zucker rats after 19 days of administration