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10.1021/pr070492f 81 VargoM
Enzymes like glutathione S-transferases (GSTs), gamma-glutamyl transferases (GTs), uridine diphospho-glucuronosyltransferases (UGTs), thiopurine methyltransferases (TPMTs), and dihydropyrimidine dehydrogenases (DPDs), with elevated levels in cancer cells, show development of MDR to a variety of anti-cancer drugs [55,56,57,58,59,60]
It makes sense to try reducing the dose and monitor weight closely
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