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This article systematically reviews the substantial impacts of LAB on macrophages, including effects on macrophage quantity, polarization, autophagy, apoptosis, metabolism, trained immunity, and so on, which contribute to the control of disease progression
Then the FDA shut it down
For skin, the three most clinically relevant effects are collagen and elastin synthesis, wound healing acceleration, and anti-inflammatory regulation
For context, heres how the most recent GLP-1 weight-loss drugs reached UK patients: Wegovy (semaglutide 2.4 mg): MHRA approval September 2021, NICE TA875 issued March 2023
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