But that changed during the Covid-19 pandemic, when Trump and conservative media pundits pushed the antimalaria drug hydroxychloroquine and antiparasitic drug ivermectin, without backing, as a cure for Covid-19
The PZQ LD 50 for NTS was determined after just 24 h exposure using both the Cell TiterGlo (27.1 2.27 M, Table 2) and the phenotypic analysis (42.9 0.83 M, Supplementary Movie 2), which is also used by others 54
Mol Cell Endocrinol 93 : 193198 Resnicoff M, Sell C, Rubini M, Coppola D, Ambrose D, Baserga R, Rubin R (1994) Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors
Together, these findings suggest a two-part model for how TB-500 might function as an anti-inflammatory agent in lab studies