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doi: 10.1038/s41419-023-05937-3 34 CorradoMPearceEL

[37] Medical uses [edit] European Union [edit] In the European Union, semaglutide is indicated for the treatment of adults with insufficiently controlled type 2 diabetes as an adjunct to diet and exercise as monotherapy when metformin is considered inappropriate due to intolerance or contraindications, [16] [17] in addition to other medicinal products for the treatment of diabetes

Vitamin B3 (Niacinamide) Strengthens the skin barrier and improves moisture retention

Experts say there are plausible albeit unconfirmed explanations, noting for example that GLP-1 medications may interfere with the efficacy of oral contraceptives or increase fertility in women because they help with weight loss