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A highly selective PET probe used for imaging the GluN2B subunit of the NMDA receptor is the benzazepine-based radioligand ( R ) - 11 C-Me-NB
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On a different angle, when subjected to DEN-induced hepatocarcinogenesis, overexpression of PGC-1 renders mice more prone to hepatocarcinoma development possibly by enhancing the expression of genes involved in fatty acids and triglycerides synthesis as well as by limiting ROS accumulation via increased antioxidant response 12
Pascual, Annette Hastie, Gregory Hawkins, Jeffrey Krings, and Regina Smith
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