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Wegovy GLP-1 receptor agonist only Average weight loss of approximately 1315% in clinical trials In head-to-head comparison, semaglutide achieved 13.7% mean weight loss at 72 weeks Often better tolerated for some individuals Zepbound Dual GIP and GLP-1 receptor agonist Average weight loss of 1521% , depending on dose 5 mg: ~15% 10 mg: ~19.5% 15 mg: ~21% In head-to-head comparison, tirzepatide achieved 20.2% mean weight loss at 72 weeks This does not mean Zepbound is universally superior

New York explicitly requires an in-person medical evaluation before prescribing any controlled substance to a patient, with only narrow exceptions (10 NYCRR 80.63, amended May 2025) (www.cchpca.org)

However, newer compounds like Dihexa and PE-22-28 have limited human safety data

Some D-SNPs may offer coverage for healthy food options through a program such as Meals on Wheels, while others may offer discounts on healthy food options at participating retailers