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The study demonstrated that MOTS-c levels in the blood of centenarians, individuals who have survived to 100 years and older, were significantly higher than in age-matched individuals with shorter lifespans, and resembled levels seen in much younger adults [2]

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INTRODUCTION Generally, neuroprotection is defined as a mechanism to maintain homeostasis and the functional integrity of the central nervous system (CNS) against any neurodegenerative and neurotoxic insults.1 Practically, neuroprotection can also refer to an intervention that helps to restore the functional integrity of the brain in response to neurobiological stress.1 Neuroprotection can be facilitated by intrinsic compensatory mechanisms and external treatment approaches

2012 Apr 15;302(8):R917-28