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Moreover, despite the considerable pre-clinical efficacy of several pharmacological agents targeting pathological events of hemorrhagic stroke, they failed to perform in clinical trials as factors such as the short half-life periods of agents and the role of the blood-brain barrier (BBB) complicated the scenario ( Based on previous studies, Wang et al., 2021)
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Genetic variation in GLP-1 receptor expression predicts gastrointestinal side effects of semaglutide
However, long-term trials are necessary to conclude the clinical safety of this peptide
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