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To address the role of the activator candidate for glutaredoxin catalysis, we replaced Lys105 of ScGrx7 by site-directed mutagenesis
This can cause tissue damage and oxidative stress
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The PDGF-BBPDGFR pathway and its downstream signaling mechanisms regulate BBB maintenance by promoting pericyte survival, proliferation, migration, differentiation, adherence to the vascular wall, and leukocyte trafficking [42, 73]
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