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The research teams modelling hints that the weight regain may plateau at 75%
Casanova, J.-L., Abel, L
A recent case report documented toxic elevations in 6-thioguanine levels following tirzepatide initiation (107)
Genetic factors may also influence the glycaemic response to GLP-1 RAs, although their impact is uncertain, while a genome-wide study did not find a link between genetic variants and weight loss response to this drug class [3], suggesting that different mechanisms are involved in the glycaemic and weight loss effects of GLP-1 RAs
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