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10.1111/j.1440-1827.2008.02250.x
GLP-1 RA treatment has been reported to increase irisin levels in patients with obesity and T2D
The researchers propose that DSIPs observed effects, particularly the selective increase in V3 and ADP/t without affecting VDNP, suggest that it does not stimulate the activity of respiratory chain enzymes or substrate transporters, as these would typically affect VDNP
At a structural level, research highlighted several features linked to methylene blue that may give it an advantage: Small molecular weight with both hydrophilic and lipophilic properties, which may help it move through different tissues once absorbed
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