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Certain genes involved in antioxidant defense, such as SOD, CAT, HO-1, and GSH, are activated, and their expression is controlled by the Nrf2antioxidant response element (ARE) pathway (Alsharif et al., 2022)

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For more information on BPNSTs, please refer to the Rare Cancers Australia Peripheral Nerve Sheath Tumours (Benign) page