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When peptides continually bind to their target receptors, the cell may internalize these receptors, modify their structure, or reduce their overall number, making the cell less responsive to subsequent peptide exposure

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Edelman S, Westerlund-Wikstrm B, Leskel S, Kettunen H, Rautonen N, Apajalahti J, Korhonen TK (2002) In vitro adhesion specificity of indigenous Lactobacilli within the avian intestinal tract