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Oral bioavailability is significantly lower than injection, so doses are typically doubled (500-1000 mcg/day vs 250-500 mcg for injection)
Firstly, the synthesis of GSH-depleted multicomponent nanomedicines is so time-consuming that it still faces a huge technological gap from laboratory preparation to industrial production ( 5 Conclusion and outlook Cancer cells show overexpressed GSH that may maintain redox homeostasis to protect cells from oxidative damage, as well as reduce the chemotherapeutic agent-induced toxification
Now their cost is no longer in the headlines, and yet their benefits are embedded all over the health ecosystem
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