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[95] Intramuscular or intravenous injection [edit] Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.51.0 mg or more), [97] [98] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire intestine by passive diffusion may be sufficient to provide a necessary amount
Allergic Reactions Though rare, some people may have an allergic reaction to the components in the B12 injection
Using Corneal Confocal Microscopy to Compare Mecobalamin Intramuscular Injections vs Oral Tablets in Treating Diabetic Peripheral Neuropathy: A RCT
NICE advises taking diagnostic blood samples before starting vitamin B12 replacement where possible
