oral semaglutide launch Novo Nordisk has received FDA approval for Wegovy® (semaglutide) 25 mg, taken once daily, making it the first oral GLP-1 drug approved for obesity. Based on OASIS and SELECT trials, it Best Semaglutide Options for 2026:

So if it turns out my experiment works, and I can get my body used to its new weight, new waistline, and new metabolism by slowing drawing down my semaglutide dose, it'll be worth the extra time I'm spending tapering now.

Elevated prolactin can cause mood changes, libido issues, and even gynecomastia in men over time

Emerging data suggest that in the context of weight loss induced by GLP-1 medications, incorporating resistance training (rather than relying solely on aerobic or walking activity) helps preserve lean mass

The 50 mg setup is far easier to draw accurately (20 units is a clean, mid-barrel mark) because the higher concentration and larger per-dose amount land on a bigger, more forgiving volume