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Key findings from the Phase 2 Randomised Controlled Trial: Adults with obesity receiving the highest 12 mg dose lost an average of 24.2 percent body weight at 48 weeks

Diabetes Obes Metab (2018) 20(1):2158

doi: McAvoy, B

Interestingly, GLP-1R knockout mice were reported to exhibit similar or increased insulin secretion compared to wild-type mice in response to glucose loads, with glucose tolerance maintained in a recent study