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A positive outcome of this trial was that selenium supplementation was well tolerated and no side effects were observed

Its selectivity and mild side effect profile make it attractive for research and niche medical applications, but the lack of robust clinical data and regulatory clarity limits its widespread adoption

Throughout the study, the mice had free access to standard laboratory granular diets and distilled water

185 While the main conventional use of progesterone and other progestogens is to mitigate the effect of estrogen therapy on the endometrium, 201 progesterone therapy alone has also been found to reduce menopausal symptoms, particularly hot flashes and sleep problems