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A comprehensive review published in Frontiers in Endocrinology (2024) further confirms that GLP-1 drugs reshape gastrointestinal physiology and metabolic regulation at multiple levels, affecting far more than just appetite
Americans of all ages have low intakes of choline: an analysis of NHANES 2009-2012 found that less than 11% of US residents ages 2 years and older had total choline intakes (from diet and supplements combined) above the AI (107)
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Together, these effects reduce appetite and make it easier to eat less without constant hunger
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