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Synthetic hormones like Premarin or Provera have a different molecular structure the body metabolizes differently
Some people naturally have: Stronger GLP-1 responses they feel full on smaller portions Weaker GLP-1 responses they feel less satisfied and stay hungry longer When GLP-1 signals are weaker, a person may feel: Hungry again soon after meals Drawn to snacks even when they just ate Like it takes a lot of food to feel satisfied This is a big reason why weight control is not just about willpower. For many people, the problem starts with the signals, not their intentions
10.1016/j.tibs.2015.02.003 Trends Biochem
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