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Acylated incretin analogs form oligomers and, in the case of the closely related semaglutide, well-characterized higher-order assemblies whose distribution shifts with pH, ionic strength and the presence of phenolic excipients
Moreover, application of the eryptosis assay for hemocompatibility in vitro testing can be helpful for identifying potential pharmaceutical agents that can target eryptosis, which can be exploitable for treating diseases associated with either accelerated or inefficient eryptosis [467]
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