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Blood and cerebrospinal-fluid metabolomics can quantify lactate/pyruvate ratios, acylcarnitines, amino-acid metabolites, NAD + -related pathways, lipid-peroxidation products, and inflammatory mediators [9, 10, 15, 16]
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New England Journal of Medicine , 384(11), 989-1002
According to this mechanism, proton transfer takes places from hydrogen peroxide to distal imidazole group, and iron-oxygen bond is generated [40]
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