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Cycle-based research structure: Epithalon studies in the literature are often structured around defined experimental cycles rather than continuous exposure

You may qualify if you have: BMI of 30 or greater (obesity) BMI of 27 or greater with at least one weight-related health condition (e.g., high blood pressure, prediabetes, high cholesterol, sleep apnea) 18 years of age or older Difficulty losing weight through diet and exercise alone No contraindications to GLP-1 medications Semaglutide may not be appropriate if you have: Personal or family history of medullary thyroid cancer or MEN2 Active pancreatitis or severe GI disorders Pregnancy or breastfeeding Severe kidney or liver disease Known allergy to semaglutide or GLP-1 medications Uncontrolled eating disorders or severe psychiatric conditions Prescription approval is not guaranteed and is based on medical necessity and provider discretion

Avoid fad diets or extreme weight loss methods, as these can be harmful and counterproductive

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