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Conclusion: Optimizing Your B12 Therapy Optimizing B12 therapy means looking at the patients health, treatment goals, and how they react to treatment
Frequency: one subcutaneous injection each day , increasing by roughly 100 mcg every 24 weeks as tolerated
Other factors include: Underlying cause of deficiency : Pernicious anaemia, malabsorption disorders, or dietary insufficiency may affect treatment response Medication use : Metformin and proton pump inhibitors can reduce gastrointestinal B12 absorption (though this does not affect the efficacy of intramuscular injections) Individual variation : Differences in how efficiently your body utilises the injected vitamin Adherence to treatment schedule : Missing injections or delaying maintenance doses can slow recovery Discussing these factors with your healthcare provider helps set realistic expectations for your treatment journey
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