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Even so, it changed modern medicine

Insulin-Like Growth Factor 1: At the Crossroads of Brain Development and Aging

Maestri, A., De Pasquale, Ceratti A., Cundari, S., Zanna, C., Cortesi, E., and Crino, L

But long-term GH replacement therapy (which produces similar GH/IGF-1 levels) has been studied for decades and is considered safe when properly monitored