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Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells
The amount used depends on the drugs guidelines
Liu Y, Morley M, Brandimarto J, Hannenhalli S, Hu Y, Ashley EA, Tang WH, Moravec CS, Margulies KB, Cappola TP
The mice were normally upright and breathing regularly within 15 min of symptom limitation and began grooming and displaying relatively normal resting behavior within the first hour
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