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Funding This work was partially supported by National Health and Medical Research Council (NHMRC) Grants GNT1105321 and GNT1012245 (P.A.W.R., G.W.M., J.E.G., S.J.H-C.), GNT1026033 (G.W.M.) and NHMRC Medical Research Future Fund GNT1199715 (P.A.W.R., M.H., S.J.H-C
Investigations remain limited to research environments and should never be interpreted as evidence of clinical or therapeutic outcomes
Trial registration This trial has been registered with ClinicalTrials.gov, number NCT 01476007, and under EUDRACT number 2010-024129-20
These findings establish BACH1 as an essential downstream effector of BPC157, forming a functional BPC157-FBXO22-BACH1 signaling axis that governs HUVEC proliferation and angiogenic capacity
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