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Younossi, MD, MPH, professor and chairman of the Global NASH/MASH Council Center for Outcomes Research in Liver Disease, told GI & Hepatology News
The colon absorbs water from stool, so longer contact can make stool drier, firmer, and harder to pass
Consequently, OPA1 mutations might facilitate stress-induced cytochrome c release by promoting the remodeling of cristae and mobilization of cytochrome c, thereby leading to RGCs degeneration
Weight loss occurs due to lessening of appetite and slowing of stomach emptying
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