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GLP-1R agonists are typically combined with metformin or other antidiabetic drugs
Additionally, disruptions in the blood-brain barrier in those with neurocognitive symptoms have been observed, as well as hypoperfusion in various organs, contributing to end-organ dysfunction [364, 365]
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Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptorG s complex
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