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Currently, the FDA has approved three GLP-1 RAs for obesity treatment: liraglutide, semaglutide and tirzepatide
It is worth noting that only a few preclinical studies have been conducted with a dose range similar to that used in human clinical settings, and most of them used doses far above the tolerated human dose
The results of the survey showed lack of consensus among practitioners regarding the desired treatment outcome
Significant reductions in HbA1c and body weight have been observed in patients taking either form of semaglutide, as supported by the American Diabetes Association
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