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Reactive microglia are positive for HLA-DR in the: Substantia nigra of Parkinsons and Alzheimers disease brains
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Further evidence demonstrates that patients with diabetes mellitus display increased atrophy in the hippocampus and amygdala compared to non-diabetic individuals, an effect not explained by increased vascular morbidity [101]
Their brains actually looked better, too, according to imaging results that showed a decrease in the excitatory neurotransmitter glutamate
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