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Bonis S
This has been demonstrated in multiple experimental models, and the anti-inflammatory effect extends beyond the gut and pancreas into the central nervous system
In clinical trials such as SURPASS and SURPASS-2, tirzepatide demonstrated comparable or superior efficacy to semaglutide in improving HbA1c and reducing BMI, with weight reductions of 5.4 to 10.5 kg and up to 2.34% HbA1c reduction at 40 weeks.16,17 Tirzepatide is administered as a weekly injection beginning at 2.5 mg weekly and increasing to 5 mg after four weeks
Large-scale randomized controlled trials meeting Western regulatory standards have not been conducted
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