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If appetite suppression leads to low energy intake over time, the body may reduce reproductive hormone signaling as a protective responsesometimes resulting in lighter, delayed, or missing periods
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Cotadutide (MedImmune, later AstraZeneca), a GLP-1/glucagon dual, showed clinically meaningful weight loss and transaminase reduction in non-alcoholic steatohepatitis - the opposite of the hepatic signal seen with antagonists
20, June 2017.
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