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GSH has a central participation in trans- hydrogenation reactions needed to maintain a reduced state of sulfhydryl groups of other molecules, proteins and enzymes, as well as formation of deoxyribonucleotides and vitamin reduction ( Glutathione brief history Glutathione was discovered in 1888 by de Rey-Pailhade and initially named philothion (from the Greek words meaning love and sulfur) because of its reactivity with sulfur to form hydrogen sulfide ( Glutathione composition and synthesis The GSH (- L-glutamyl-L-cysteinyl-glycine) is a water-soluble tripeptide formed by the amino-acids glutamic acid, cysteine and glycine (Figure 1) present in the cytoplasm of all cells
Die Folge kann eine erhhte Infektanflligkeit sein
doi: 10.1002/hep.27490 118 WattMJBarnettACBruceCRSchenkSHorowitzJFHoyAJ
In IBD, the expression levels of tight junction proteins such as ZO-1 and Occludin, is generally suppressed, leading to increased intestinal permeability, enhanced pathogen infiltration, and exacerbated inflammatory responses (Dong et al., 2022)
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