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If a patients mitochondria are not effectively converting stored fat into usable energy, blocking their appetite will only result in fatigue and muscle catabolism
After serum limitation-induction, positive FOXO4 and p53-pS15 immunofluorescence staining was stronger in the nucleus of keloid fibroblasts at 48 h, but in the nucleus of normal skin fibroblasts at 72 h
doi: 10.1186/1477-7827-8-12 82 RicciGPerticarariSFragonasEGioloECanovaSPozzobonCet al
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