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Improve blood sugar control Reduce the risk of heart attack and stroke (along with a reduced calorie diet and increased physical activity) There is some evidence that GLP-1 may also reduce cravings and change food preferences, possibly by acting on reward centers in the brain
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It incorporates key modifications, including 14E/17R mutations to stabilize an -helical segment via a salt bridge, multiple proline substitutions (25P, 28P, 29P) to reduce -sheet formation, and N-terminal C20 fatty diacid lipidation for reversible albumin binding (Kruse et al
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